Gardasil Study Funded by Merck: Are Results Biased?;
CBCD Raises Doubts
This study was funded by Merck, the manufacturer
of Gardasil. Many scientific papers argue that the public should not trust any
industry funded research.
The Center for the Biology of Chronic Disease (CBCD) has learned
that Merck recently funded a study conducted by Dr. Chun Chao from Kaiser
Permanente. USA Today reported: "Study: No link between HPV vaccine and
autoimmune disorders" on January 28, 2012. In the opening paragraph, the story
says that "The human papillomavirus (HPV) vaccine Gardasil does not trigger
Should the reader believe the report? Is it possible that the
researchers, who conducted the study, are biased?
According to USA Today, this study was funded by Merck, the
manufacturer of Gardasil. Many scientific papers argue that the public should
not trust any industry funded research.
For instance, a paper published in the Indian Journal of Medical
Ethics says that, "Empirical research indicates that much of the evidence
required for the practice of evidence-based medicine cannot be trusted. The
research agenda has been hijacked by those with vested interests within industry
and academia, determining what research is funded and how it is done and
reported." It went on to say, "Many well-reported randomized controlled trials
are designed to deceive by their choice of comparators and outcomes...."
Another paper published in the American Journal of Orthopedics
says, " ...industry-sponsored clinical trials have traditionally been associated
with more positive results."
Yet another paper published in Science and Engineering Ethics says,
"Pharmaceutical companies fund the bulk of clinical research that is carried out
on medications. Poor outcomes from these studies can have negative effects on
sales of medicines. Previous research has shown that company funded research is
much more likely to yield positive outcomes than research with any other
Finally, a paper in PLoS ONE quotes Dr. Daniele Fanelli as writing,
"about 2% of scientists admitted to have fabricated, falsified or modified data
or results at least once - a serious form of misconduct by any standard - and up
to one third admitted a variety of other questionable research practices
including "dropping data points based on a gut feeling," and "changing the
design, methodology or results of a study in response to pressures from a
What do these papers say in simple terms?
When a company pays for the study, beware. The results usually show
what the company wants them to show. In other words, those who have the gold,
somehow, determine the results.
In this case, the company with the gold is Merck, and the product
is Gardasil. It is certainly within Merck's interests to disprove any connection
between their vaccine and autoimmune disorders. And lo and behold! The results
promote Merck's interest.
Merck's funded study relies on correlation, a weak approach at
best. The CBCD would like to suggest another method for answering the question
about Gardasil and disease. It is called the mechanistic approach. In simple
terms it is answering the following question, "If Gardasil causes disease, what
is the biological mechanism that leads from getting the Gardasil shot to
Dr. Hanan Polansky's discovery of "Microcompetition with Foreign
DNA" provides such a biological mechanism. Microcompetition explains how the DNA
fragments found in the Gardasil vaccine can cause major diseases, including
Dr. Hanan Polansky is the author of the highly acclaimed "Purple"
book, entitled Microcompetition with Foreign DNA and the Origin of Chronic
Disease. In his book he explains how foreign DNA fragments can cause many major
diseases without damaging (mutating) the human DNA.
"Not only does the book present a strong theory to unify the cause
of many diverse disease states, the book itself represents an aspect lacking in
the field of medical science, an attempt to unify observations into coherent
theories." - Q. Ping Dou, PhD - Co-Leader, Prevention Program, Barbara Ann
Karmanos Cancer Institute, and Professor, Department of Pathology, School of
Medicine, Wayne State University
The book has been read by more than 5,000 scientists around the
world, and has been reviewed in more than 20 leading scientific journals such as
the Archives of Virology and the European Journal of Cancer.
The CBCD encourages biologists, virologists, geneticists,
scientists and the general public to obtain a copy of Dr. Hanan Polansky's book
and read it. The book is available as a free download from the CBCD website.
The CBCD endorses Dr. Polansky's theory, and invites the media,
scientists, and the general public to contact us on this issue.
For more information on the Center for the Biology of Chronic
Disease, or to schedule an interview with Dr. Polansky, please visit
http://www.cbcd.net or call 585-250-9999.
Tharyan P. "Evidence-based medicine: can the evidence be trusted?"
Indian Journal of Medical Ethics, Oct., 2011
Lexchin J. "Those Who Have the Gold Make the Evidence: How the
Pharmaceutical Industry Biases the Outcomes of Clinical Trials of Medications."
Science and Engineering Ethics, February 15, 2011
Fanelli D. "How many scientists fabricate and falsify research? A
systematic review and meta-analysis of survey data." PLoS ONE, May 29, 2009
Khan SN, Mermer MJ, Myers E, Sandhu HS. "The roles of funding
source, clinical trial outcome, and quality of reporting in orthopedic surgery
literature." American Journal of Orthopedics (Belle Meade N.J.) Dec., 2008